A man suffering from erectile dysfunction might prevent the breakdown of CGMP by simply preventing the operations of PDE-5 enzymes. This could be achieved if the guy took even one medication, preferably an hour before engaging in sexual activity. A man's body will often release nitric oxide during acts of sensual stimulation, which can then produce cGMP. Male genital tract corpus cavernosum can become overexposed to cGMP, which dilates the blood vessels there. Harder erections will follow as a result of a more noticeable blood flow into and towards the male genitalia.

Men's erectile dysfunction can be significantly improved by using the highly effective medication Cenforce 100 mg. This medication has sildenafil citrate as its primary constituent. It is an active PDE type 5 inhibitor that works wonders for issues relating to male impotence.